AB-Bind
Antibody-focused mutational binding data with accompanying structures for computational affinity prediction.
Scientific domain
Protein-protein binding
Protein-protein interaction
蛋白-蛋白结合
19 registered benchmarks and tracks
AbBiBench
A framework using antibody–antigen complexes to evaluate affinity prediction and antibody redesign.
ATOM3D
A living collection of eight curated 3D molecular-learning tasks spanning small molecules, protein interactions and mutations, ligand binding, and protein/RNA structure ranking.
Biology-Instructions
A multi-omics sequence-instruction suite with 21 formal predictive tasks across DNA, RNA, protein, and multi-molecule inputs; the final paper reports task-specific held-out evaluations rather than a single aggregate score.
Biology-Instructions Antibody-Antigen Neutralization
Binary neutralization prediction for an antibody-antigen protein-sequence pair, evaluated with Matthews correlation coefficient.
CaM benchmark
A multistate protein sequence-design benchmark spanning CaM conformations and binding modes.
CAMEO
Weekly, automated, independent, blind evaluation of registered macromolecular structure-prediction servers on complete PDB entries whose experimental structures are withheld during prediction.
CASP
Biennial blind community experiments that assess macromolecular structure, complex, ligand, and model-accuracy prediction against experimental structures withheld during prediction.
CASP17 Immune Complexes
Dedicated CASP17 category for blind prediction of antibody-antigen, nanobody-antigen, and T-cell receptor complex structures.
CASP Protein Multimers
Formal CASP track assessing blind protein-complex predictions, including overall folds, interfaces, stoichiometry-free phases, and model-selection phases.
FLIP
A supervised protein sequence-to-fitness benchmark that turns three experimental landscapes into 15 biologically motivated dataset splits for testing generalization in protein engineering.
FLIP GB1
Five supervised splits over a downsampled, highly epistatic four-site GB1 immunoglobulin-binding landscape, designed to test mutation-depth and low-to-high-fitness generalization.
LAB-Bench
A practical biology-research suite of 2,457 multiple-choice questions across eight broad categories and 31 versioned task files, with public and private contamination-monitoring splits.
LAB-Bench DbQA
Database-retrieval category spanning 10 genomics, clinical, protein, regulatory, vaccine-response, and viral-PPI tasks.
LAB-Bench DbQA — Viral protein–protein interactions
Retrieves predicted human interaction partners of viral proteins from P-HIPSter.
LifeSciBench
Expert-authored, artifact-rich free-response tasks that evaluate realistic research judgment across applied life-science workflows.
PapD benchmark
A multistate protein sequence-design benchmark targeting the multispecific PapD binding interface.
PPB-Affinity
A reusable protein-protein binding-affinity dataset with complex structures, measured affinities, receptor and ligand chains, and mutation annotations.
ProteinLMBench
A creator-curated set of 944 protein-science multiple-choice questions with answer explanations, generated from research literature and released for evaluating text LLM protein understanding.
Capability coverage
Registry records tagged Protein-protein binding, counted by capability.
Accessible data table
| Capability | Records |
|---|---|
| Knowledge | 4 |
| Evidence synthesis | 2 |
| Retrieval | 4 |
| Prediction | 16 |
| Classification | 6 |
| Regression | 5 |
| Design | 5 |
| Generation | 2 |
| Optimization | 5 |
| Data analysis | 2 |
| Tool use | 1 |
| Experiment planning | 2 |
| Troubleshooting | 2 |
| Scientific reasoning | 5 |
| Scientific communication | 1 |
Scientific Tasks in this domain
Task mappings are evidence-backed and may be partial for mixed suites.
Coverage-gap reading: zero counts indicate a gap in this registry, not proof that no benchmark exists. Propose a primary source through the contribution form.