Scientific task · Design and generation

Protein sequence design

Generate an amino-acid sequence satisfying specified structural or functional constraints.

蛋白质序列设计

ProteinDesign and generation

Definition and search aliases

Permanent ID
protein-sequence-design
Aliases
sequence generation, inverse folding
Deprecated aliases
None
Hierarchy
Leaf task under Protein design

Coverage

3 benchmark families cover this task

datasetpartial

CaM benchmark

A multistate protein sequence-design benchmark spanning CaM conformations and binding modes.

Protein sequence design
datasetpartial

PapD benchmark

A multistate protein sequence-design benchmark targeting the multispecific PapD binding interface.

Protein sequence design
datasetpartial

RfaH benchmark

A multistate protein sequence-design benchmark using the fold-switching conformations of RfaH.

Protein sequence design

Evidence-backed count claims

Each row keeps its original unit and basis. Rows with different units or overlapping mappings are never added.

BenchmarkMapped taskCoverageCountVersionEvidence
Biology-Instructions
root: bioinstruction
Protein sequence design
official-taxonomy · high
not-in-scope0 tracks
Formal evaluation tracks in the final creator paper.
emnlp-2025bioinstruction-evidence-paper
CaM benchmark
root: cam-benchmark
Protein sequence design
official-taxonomy · high
explicitly-in-scopeNot reported
Creator-defined multistate protein sequence-design benchmark system.
initial-releasecam-benchmark-automated-metadata-2-evidence
LAB-Bench
root: lab-bench
Protein sequence design
official-taxonomy · high
not-in-scope0 questions
Released LAB-Bench questions.
repository-998a8e0lab-bench-evidence-paper
PapD benchmark
root: papd-benchmark
Protein sequence design
official-taxonomy · high
explicitly-in-scopeNot reported
Creator-defined multistate protein sequence-design benchmark system.
initial-releasepapd-benchmark-automated-metadata-2-evidence
RfaH benchmark
root: rfah-benchmark
Protein sequence design
official-taxonomy · high
explicitly-in-scopeNot reported
Creator-defined multistate protein sequence-design benchmark system.
initial-releaserfah-benchmark-automated-metadata-2-evidence

Official evaluations connected to these benchmarks

Runs are included only for benchmark records mapped here (and formal child tracks when a mapped suite is the root). A task mapping does not imply that every run isolates this task.

No normalized official evaluation run is connected to the mapped benchmark records yet.