BEACON
A 13-task RNA representation benchmark covering structure, function, processing, modification, translation, degradation, programmable switches, and CRISPR activity.
Scientific task · Variant and perturbation effect
CRISPR guide activity prediction
Predict on-target activity or efficiency of a CRISPR guide sequence.
CRISPR向导活性预测
Nucleic-acid result atlas: T55 results (composite)
Definition and search aliases
- Permanent ID
crispr-guide-activity-prediction- Aliases
- CRISPR on-target prediction
- Deprecated aliases
- None
- Hierarchy
- Leaf task under DNA regulation and perturbation
Coverage
2 benchmark families cover this task
Biology-Instructions
A multi-omics sequence-instruction suite with 21 formal predictive tasks across DNA, RNA, protein, and multi-molecule inputs; the final paper reports task-specific held-out evaluations rather than a single aggregate score.
Biology-Instructions CRISPR On-Target Prediction
Regression of CRISPR guide on-target activity from an RNA sequence, evaluated with Spearman rank correlation.
Evidence-backed count claims
Each row keeps its original unit and basis. Rows with different units or overlapping mappings are never added.
| Benchmark | Mapped task | Coverage | Count | Version | Evidence |
|---|---|---|---|---|---|
| BEACON root: beacon-rna | CRISPR guide activity prediction official-taxonomy · high | explicitly-in-scope | 1 tasks Formal RNA benchmark tasks. | neurips-2024 | beacon-paper-definition-evidence |
| Biology-Instructions root: bioinstruction | CRISPR guide activity prediction official-track · high | explicitly-in-scope | 1 tracks Formal evaluation tracks (CRISPR On-Target Prediction). | emnlp-2025 | bioinstruction-evidence-paper |
| Biology-Instructions CRISPR On-Target Prediction root: bioinstruction | CRISPR guide activity prediction official-track · high | explicitly-in-scope | 2076 examples distinct examples across the published train, validation, and test splits | emnlp-2025 | bioinstruction-crispr-on-target-evidence-paper |
Official evaluations connected to these benchmarks
Runs are included only for benchmark records mapped here (and formal child tracks when a mapped suite is the root). A task mapping does not imply that every run isolates this task.