基因组元件分类
Genomic element classification
Classify sequence windows as promoters, enhancers, exons, introns or other genomic elements.
- Benchmarks
- 6
- 协议
- 8
- 映射状态
- 已覆盖
任务体系
58 个核酸任务，全部已连接 benchmark。
从生物学问题出发，查看对应 benchmark、track 和严格对齐的评测协议。
58 / 58 个任务
启动子识别
Promoter recognition
Recognize promoter sequence windows; promoter activity is counted separately under D3.
- Benchmarks
- 6
- 协议
- 9
- 映射状态
- 已覆盖
增强子识别
Enhancer recognition
Recognize enhancer sequence windows independent of quantitative activity.
- Benchmarks
- 5
- 协议
- 10
- 映射状态
- 已覆盖
转录因子结合位点预测
TF binding-site prediction
Predict sequence-specific TF occupancy or binding sites.
- Benchmarks
- 7
- 协议
- 0
- 映射状态
- 已覆盖
染色质可及性预测
Chromatin accessibility prediction
Predict cell-type-specific accessible chromatin from DNA sequence.
- Benchmarks
- 4
- 协议
- 1
- 映射状态
- 已覆盖
组蛋白修饰预测
Histone-mark prediction
Predict histone-mark assay signal from sequence.
- Benchmarks
- 3
- 协议
- 41
- 映射状态
- 已覆盖
剪接位点识别
Splice-site prediction
Predict splice donor and acceptor positions.
- Benchmarks
- 8
- 协议
- 18
- 映射状态
- 已覆盖
可变剪接模式识别
Alternative splicing pattern prediction
Predict splice pattern or exon inclusion without a specific variant perturbation.
- Benchmarks
- 2
- 协议
- 3
- 映射状态
- 已覆盖
多聚腺苷酸化位点识别
Polyadenylation-site prediction
Locate or rank polyadenylation sites.
- Benchmarks
- 1
- 协议
- 3
- 映射状态
- 已覆盖
非编码 RNA 家族分类
ncRNA family classification
Assign ncRNA sequences to functional families.
- Benchmarks
- 7
- 协议
- 2
- 映射状态
- 已覆盖
RNA 修饰位点预测
RNA modification-site prediction
Predict modification status at candidate nucleotides.
- Benchmarks
- 3
- 协议
- 1
- 映射状态
- 已覆盖
RNA 亚细胞定位
RNA subcellular localization
Predict RNA localization from sequence or sequence-derived representations.
- Benchmarks
- 1
- 协议
- 3
- 映射状态
- 已覆盖
序列基序发现
Sequence motif discovery
Recover interpretable motifs rather than only predictive scores.
- Benchmarks
- 1
- 协议
- 0
- 映射状态
- 已覆盖
RNA 二级结构配对预测
RNA secondary-structure base-pair prediction
Predict base pairs or dot-bracket secondary structure.
- Benchmarks
- 5
- 协议
- 40
- 映射状态
- 已覆盖
RNA 非经典碱基对预测
RNA non-canonical base-pair prediction
Predict non-canonical pair identities and contacts.
- Benchmarks
- 1
- 协议
- 0
- 映射状态
- 已覆盖
RNA 接触/距离图预测
RNA contact or distance-map prediction
Predict pairwise contacts or distances without full coordinates.
- Benchmarks
- 2
- 协议
- 3
- 映射状态
- 已覆盖
RNA 三维坐标预测
RNA 3D coordinate prediction
Predict RNA 3D coordinates from sequence and optional auxiliary inputs.
- Benchmarks
- 5
- 协议
- 81
- 映射状态
- 已覆盖
DNA 局部形状预测
DNA shape prediction
Predict local DNA shape features.
- Benchmarks
- 1
- 协议
- 0
- 映射状态
- 已覆盖
染色质三维接触预测
3D genome contact prediction
Predict Hi-C-like contact patterns from long sequence.
- Benchmarks
- 2
- 协议
- 1
- 映射状态
- 已覆盖
RNA 结构探针反应性预测
RNA probing-reactivity prediction
Predict chemical probing reactivity.
- Benchmarks
- 5
- 协议
- 21
- 映射状态
- 已覆盖
RNA 三维模型质量评估
RNA 3D model quality assessment
Rank or score candidate RNA 3D models.
- Benchmarks
- 6
- 协议
- 0
- 映射状态
- 已覆盖
RNA 构象集合预测
RNA conformational ensemble prediction
Predict multiple conformers or a conformational distribution.
- Benchmarks
- 1
- 协议
- 0
- 映射状态
- 已覆盖
核酸全原子复合物结构预测
All-atom nucleic-acid complex structure prediction
Predict complexes containing DNA/RNA and proteins, ligands or other nucleic acids.
- Benchmarks
- 4
- 协议
- 2
- 映射状态
- 已覆盖
启动子活性预测
Promoter activity prediction
Predict quantitative promoter activity.
- Benchmarks
- 1
- 协议
- 0
- 映射状态
- 已覆盖
增强子活性预测
Enhancer activity prediction
Predict quantitative enhancer activity, often cell-type specific.
- Benchmarks
- 1
- 协议
- 0
- 映射状态
- 已覆盖
序列到基因表达预测
Sequence-to-gene-expression prediction
Predict expression from cis-regulatory DNA context.
- Benchmarks
- 2
- 协议
- 1
- 映射状态
- 已覆盖
mRNA 稳定性/半衰期预测
mRNA stability or half-life prediction
Predict RNA abundance decay or half-life.
- Benchmarks
- 1
- 协议
- 0
- 映射状态
- 已覆盖
翻译效率/核糖体负载预测
Translation efficiency or ribosome-load prediction
Predict mean ribosome loading or translation efficiency.
- Benchmarks
- 5
- 协议
- 2
- 映射状态
- 已覆盖
可变加尾定量
Alternative polyadenylation quantification
Predict relative poly(A) site usage.
- Benchmarks
- 2
- 协议
- 1
- 映射状态
- 已覆盖
RNA 降解/疫苗稳定性预测
RNA degradation and vaccine-stability prediction
Predict degradation-related measurements as in OpenVaccine.
- Benchmarks
- 2
- 协议
- 10
- 映射状态
- 已覆盖
核酶活性预测
Ribozyme activity prediction
Predict activity of ribozymes or catalytic RNAs.
- Benchmarks
- 1
- 协议
- 0
- 映射状态
- 已覆盖
可编程 RNA 开关功能预测
Programmable RNA-switch function prediction
Predict function of toehold or related RNA switches.
- Benchmarks
- 1
- 协议
- 1
- 映射状态
- 已覆盖
核酸适应度预测
Nucleic-acid fitness prediction
Predict assay-specific sequence fitness; mutation-specific RNA DMS is cross-referenced to D4.
- Benchmarks
- 2
- 协议
- 2
- 映射状态
- 已覆盖
调控变异效应预测
Regulatory variant-effect prediction
Predict effects of non-coding variants on regulatory activity.
- Benchmarks
- 4
- 协议
- 3
- 映射状态
- 已覆盖
表达变异效应预测
Expression variant-effect prediction
Predict variant-induced expression changes.
- Benchmarks
- 1
- 协议
- 1
- 映射状态
- 已覆盖
剪接变异效应预测
Splicing variant-effect prediction
Predict variant effects on splicing.
- Benchmarks
- 1
- 协议
- 0
- 映射状态
- 已覆盖
RNA 结合变异效应预测
RNA-binding variant-effect prediction
Predict variant effects on RBP binding.
- Benchmarks
- 1
- 协议
- 3
- 映射状态
- 已覆盖
RNA 深度突变扫描效应预测
RNA DMS effect prediction
Predict mutation effects across RNA deep-mutational-scanning assays.
- Benchmarks
- 3
- 协议
- 2
- 映射状态
- 已覆盖
分子功能性/致病变异解释
Molecular functional or pathogenic variant interpretation
Restricted here to molecular/functional challenges; patient-level diagnosis and PRS are excluded.
- Benchmarks
- 2
- 协议
- 2
- 映射状态
- 已覆盖
进化约束与保守性预测
Evolutionary constraint and conservation prediction
Predict evolutionary constraint at nucleotide resolution.
- Benchmarks
- 1
- 协议
- 0
- 映射状态
- 已覆盖
转录因子–DNA 结合特异性
TF–DNA binding specificity
Predict TF–DNA specificity across factors and sequences.
- Benchmarks
- 2
- 协议
- 0
- 映射状态
- 已覆盖
RNA–蛋白结合预测
RNA–protein binding prediction
Predict RBP–RNA binding or binding sites.
- Benchmarks
- 3
- 协议
- 23
- 映射状态
- 已覆盖
RNA–RNA 相互作用预测
RNA–RNA interaction prediction
Predict intermolecular RNA pairing or interaction.
- Benchmarks
- 1
- 协议
- 7
- 映射状态
- 已覆盖
RNA–小分子结合预测
RNA–small-molecule binding prediction
Predict whether and how strongly small molecules bind RNA.
- Benchmarks
- 5
- 协议
- 0
- 映射状态
- 已覆盖
适配体–靶标亲和力预测
Aptamer–target affinity prediction
Predict aptamer binding to proteins or other targets.
- Benchmarks
- 2
- 协议
- 3
- 映射状态
- 已覆盖
核酸–蛋白界面/对接预测
Nucleic-acid–protein interface or docking
Predict interaction interface or relative pose.
- Benchmarks
- 3
- 协议
- 2
- 映射状态
- 已覆盖
核酸–小分子对接
Nucleic-acid–small-molecule docking
Predict ligand poses in nucleic-acid targets.
- Benchmarks
- 3
- 协议
- 0
- 映射状态
- 已覆盖
启动子序列设计
Promoter sequence design
Design promoters for a target activity.
- Benchmarks
- 1
- 协议
- 1
- 映射状态
- 已覆盖
增强子/顺式调控元件设计
Enhancer or cis-regulatory design
Design cis-regulatory sequences for desired activity.
- Benchmarks
- 1
- 协议
- 0
- 映射状态
- 已覆盖
5′UTR 与翻译调控设计
5′UTR and translation-control design
Design 5′UTRs for target translation.
- Benchmarks
- 1
- 协议
- 0
- 映射状态
- 已覆盖
mRNA 编码与稳定性协同设计
mRNA coding and stability co-design
Design coding and untranslated regions jointly under therapeutic constraints.
- Benchmarks
- 1
- 协议
- 0
- 映射状态
- 已覆盖
RNA 二级结构逆折叠
RNA secondary-structure inverse folding
Generate sequences expected to fold into a target secondary structure.
- Benchmarks
- 1
- 协议
- 1
- 映射状态
- 已覆盖
RNA 三维结构条件设计
RNA 3D-conditioned design
Generate sequences conditioned on a target tertiary structure.
- Benchmarks
- 2
- 协议
- 0
- 映射状态
- 已覆盖
适配体设计
Aptamer design
Generate aptamers for a chosen target.
- Benchmarks
- 1
- 协议
- 0
- 映射状态
- 已覆盖
CRISPR 向导 RNA 靶向效率设计
CRISPR guide on-target design
Design guides for high on-target efficiency.
- Benchmarks
- 1
- 协议
- 8
- 映射状态
- 已覆盖
CRISPR 脱靶风险设计
CRISPR guide off-target design
Design or rank guides to minimize off-target activity.
- Benchmarks
- 1
- 协议
- 1
- 映射状态
- 已覆盖
siRNA/ASO/shRNA 设计
siRNA, ASO or shRNA design
Design therapeutic oligonucleotides; chemistries remain dataset-specific.
- Benchmarks
- 1
- 协议
- 24
- 映射状态
- 已覆盖
可编程 RNA 开关设计
Programmable RNA-switch design
Design RNA switches or sensors with target response.
- Benchmarks
- 1
- 协议
- 0
- 映射状态
- 已覆盖
没有符合当前筛选条件的任务。