OligoGym
Twelve curated ASO/siRNA/shRNA datasets with explicit split comparisons.
24 个 benchmark 数值协议 · 45,932 条 benchmark 全局结果（非 task 小计）D6 · 生成与设计
siRNA/ASO/shRNA 设计
Design therapeutic oligonucleotides; chemistries remain dataset-specific.
siRNA, ASO or shRNA design
任务定义
- 输入粒度
- target transcript
- 生物学目标
- knockdown potency and safety
- 输出表示
- oligo sequence/rank
- ML formulation
- ranking/optimization
- 计数说明
- NR
Benchmark coverage
1 个 benchmark 覆盖该任务
评测协议
24 个口径单元
| Protocol | Track | Split / subset | 可比状态 |
|---|---|---|---|
PROT-B27-OLIGOGYM-F36E039C1F1610F9 | acute_neurotox_lna | nucleobase B27-TR01 | official five-fold nucleobase cross-validation acute_neurotox_lna | same_table_comparable inference_budget;canonical dataset alias mapping;featurizer-specific external pretraining differs |
PROT-B27-OLIGOGYM-F88A0FA5C042F1EF | acute_neurotox_lna | random B27-TR01 | official five-fold random cross-validation acute_neurotox_lna | same_table_comparable inference_budget;canonical dataset alias mapping;featurizer-specific external pretraining differs |
PROT-B27-OLIGOGYM-98A4867D831244B6 | acute_neurotox_moe_cleaned | nucleobase B27-TR01 | official five-fold nucleobase cross-validation acute_neurotox_moe_cleaned | same_table_comparable inference_budget;canonical dataset alias mapping;featurizer-specific external pretraining differs |
PROT-B27-OLIGOGYM-7EBD66FE672FF9E0 | acute_neurotox_moe_cleaned | random B27-TR01 | official five-fold random cross-validation acute_neurotox_moe_cleaned | same_table_comparable inference_budget;canonical dataset alias mapping;featurizer-specific external pretraining differs |
PROT-B27-OLIGOGYM-289604CE95A797E9 | asoptimizer_cleaned | nucleobase B27-TR01 | official five-fold nucleobase cross-validation asoptimizer_cleaned | same_table_comparable inference_budget;canonical dataset alias mapping;featurizer-specific external pretraining differs |
PROT-B27-OLIGOGYM-CE31CDB64D238086 | asoptimizer_cleaned | random B27-TR01 | official five-fold random cross-validation asoptimizer_cleaned | same_table_comparable inference_budget;canonical dataset alias mapping;featurizer-specific external pretraining differs |
PROT-B27-OLIGOGYM-628151F0D4F1D263 | cytotox_lna | nucleobase B27-TR01 | official five-fold nucleobase cross-validation cytotox_lna | same_table_comparable inference_budget;canonical dataset alias mapping;featurizer-specific external pretraining differs |
PROT-B27-OLIGOGYM-889C99B7B65E84F5 | cytotox_lna | random B27-TR01 | official five-fold random cross-validation cytotox_lna | same_table_comparable inference_budget;canonical dataset alias mapping;featurizer-specific external pretraining differs |
PROT-B27-OLIGOGYM-507177AA6D1DD43A | immune_modulation_TLR7 | nucleobase B27-TR01 | official five-fold nucleobase cross-validation immune_modulation_TLR7 | same_table_comparable inference_budget;canonical dataset alias mapping;featurizer-specific external pretraining differs |
PROT-B27-OLIGOGYM-292B97F2F9FC127A | immune_modulation_TLR7 | random B27-TR01 | official five-fold random cross-validation immune_modulation_TLR7 | same_table_comparable inference_budget;canonical dataset alias mapping;featurizer-specific external pretraining differs |
PROT-B27-OLIGOGYM-DE16184F64229A78 | immune_modulation_TLR8 | nucleobase B27-TR01 | official five-fold nucleobase cross-validation immune_modulation_TLR8 | same_table_comparable inference_budget;canonical dataset alias mapping;featurizer-specific external pretraining differs |
PROT-B27-OLIGOGYM-73DEAE0406D1EB54 | immune_modulation_TLR8 | random B27-TR01 | official five-fold random cross-validation immune_modulation_TLR8 | same_table_comparable inference_budget;canonical dataset alias mapping;featurizer-specific external pretraining differs |
PROT-B27-OLIGOGYM-3CAE47A8912718F0 | openASO | nucleobase B27-TR01 | official five-fold nucleobase cross-validation openASO | same_table_comparable inference_budget;canonical dataset alias mapping;featurizer-specific external pretraining differs |
PROT-B27-OLIGOGYM-5E00C233C1911A54 | openASO | random B27-TR01 | official five-fold random cross-validation openASO | same_table_comparable inference_budget;canonical dataset alias mapping;featurizer-specific external pretraining differs |
PROT-B27-OLIGOGYM-7D5A0FEF9849C754 | sherwood | nucleobase B27-TR01 | official five-fold nucleobase cross-validation sherwood | same_table_comparable inference_budget;canonical dataset alias mapping;featurizer-specific external pretraining differs |
PROT-B27-OLIGOGYM-F867B5AE44BAFA76 | sherwood | random B27-TR01 | official five-fold random cross-validation sherwood | same_table_comparable inference_budget;canonical dataset alias mapping;featurizer-specific external pretraining differs |
PROT-B27-OLIGOGYM-7389ACA248034714 | siRNA1 | nucleobase B27-TR01 | official five-fold nucleobase cross-validation siRNA1 | same_table_comparable inference_budget;canonical dataset alias mapping;featurizer-specific external pretraining differs |
PROT-B27-OLIGOGYM-76CE1FD6B8912426 | siRNA1 | random B27-TR01 | official five-fold random cross-validation siRNA1 | same_table_comparable inference_budget;canonical dataset alias mapping;featurizer-specific external pretraining differs |
PROT-B27-OLIGOGYM-6998E690661BBFEA | siRNA2 | nucleobase B27-TR01 | official five-fold nucleobase cross-validation siRNA2 | same_table_comparable inference_budget;canonical dataset alias mapping;featurizer-specific external pretraining differs |
PROT-B27-OLIGOGYM-2073AA243372A7C0 | siRNA2 | random B27-TR01 | official five-fold random cross-validation siRNA2 | same_table_comparable inference_budget;canonical dataset alias mapping;featurizer-specific external pretraining differs |
PROT-B27-OLIGOGYM-3DBE3CE543ADE8FD | siRNA3 | nucleobase B27-TR01 | official five-fold nucleobase cross-validation siRNA3 | same_table_comparable inference_budget;canonical dataset alias mapping;featurizer-specific external pretraining differs |
PROT-B27-OLIGOGYM-4577ECB580203740 | siRNA3 | random B27-TR01 | official five-fold random cross-validation siRNA3 | same_table_comparable inference_budget;canonical dataset alias mapping;featurizer-specific external pretraining differs |
PROT-B27-OLIGOGYM-156A35B4BB5CB995 | siRNAmod | nucleobase B27-TR01 | official five-fold nucleobase cross-validation siRNAmod | same_table_comparable inference_budget;canonical dataset alias mapping;featurizer-specific external pretraining differs |
PROT-B27-OLIGOGYM-BD3402033525D1C0 | siRNAmod | random B27-TR01 | official five-fold random cross-validation siRNAmod | same_table_comparable inference_budget;canonical dataset alias mapping;featurizer-specific external pretraining differs |