RNA 结合变异效应预测

Predict variant effects on RBP binding.

RNA-binding variant-effect prediction

任务定义

输入粒度: variant plus RNA context
生物学目标: RBP binding change
输出表示: delta binding score
ML formulation: regression/ranking
计数说明: NR

Benchmark coverage

1 个 benchmark 覆盖该任务

B43有公开数值结果

RNP-ΔΔG blind mutation benchmark

Blind and independent RNA–protein affinity tests; only RNA-side mutations are in scope. MS2, diverse-complex and PUM2 tests remain separate protocols.

3 个 benchmark 数值协议 · 3 条 benchmark 全局结果（非 task 小计）

评测协议

3 个口径单元

Protocol	Track	Split / subset	可比状态
`P-B43-ALL6`	six-system retrospective aggregate B43-TR01	retrospective independent systems all six tested systems	same_table_comparable NR
`P-B43-PUM2-R2-528`	PUM2 blind round 2 B43-TR01	blind predictions; independent measurement 528 sequences across four scaffolds	same_table_comparable NR
`P-B43-PUM2-R2-385`	PUM2 blind round-2 subset B43-TR01	blind predictions; independent measurement 385 sequences without mutations at position 5	same_table_comparable NR