Biology-Instructions
A multi-omics sequence-instruction suite with 21 formal predictive tasks across DNA, RNA, protein, and multi-molecule inputs; the final paper reports task-specific held-out evaluations rather than a single aggregate score.
Scientific domain
Epigenomics
DNA methylation
表观组学
15 registered benchmarks and tracks
Biology-Instructions Enhancer Activity Prediction
Two-output regression of housekeeping and developmental enhancer activity from a DNA sequence, evaluated with separate Pearson correlations.
Biology-Instructions Epigenetic Marks Prediction
Binary prediction of whether a DNA sequence carries an epigenetic mark, evaluated with Matthews correlation coefficient.
Biology-Instructions Enhancer-Promoter Interaction Prediction
Binary interaction prediction for enhancer and promoter DNA sequences, evaluated with Matthews correlation coefficient.
Biology-Instructions RNA Modification Prediction
Multi-label prediction of RNA chemical modifications, evaluated with macro area under the ROC curve.
BioMysteryBench
An agentic bioinformatics benchmark of objective, expert-authored mysteries over anonymized real-world biological data, scored on final answers rather than prescribed analysis paths.
BixBench
A containerized benchmark of long-horizon bioinformatics analysis over real published notebooks and associated data, with open-answer and multiple-choice evaluation modes.
CompBioBench
A 100-task agent benchmark of objectively gradable computational-biology problems requiring multi-step reasoning, bespoke code, tools, and real-world external resources.
GeneBench-Pro
A research-level agent benchmark of 129 synthetic, multistage computational-biology analyses that require iterative QC, statistical modeling, diagnostics, and decision-relevant judgment.
Genomic Benchmarks
A versioned collection of nine DNA sequence-classification datasets covering regulatory elements, promoters, enhancers, open chromatin, species, and coding-context discrimination.
LAB-Bench
A practical biology-research suite of 2,457 multiple-choice questions across eight broad categories and 31 versioned task files, with public and private contamination-monitoring splits.
LAB-Bench DbQA
Database-retrieval category spanning 10 genomics, clinical, protein, regulatory, vaccine-response, and viral-PPI tasks.
LAB-Bench DbQA — GTRD transcription-factor binding sites
Retrieves promoter-region transcription-factor binding-site annotations from GTRD.
scIB
A 13-task benchmark of single-cell data integration across simulated, scRNA-seq, and scATAC-seq settings, evaluated with 14 batch-removal and biological-conservation metrics.
Single-cell Omics Arena
A benchmark for evaluating LLM cell-type annotation across scRNA-seq and single-cell multiomics data.
Capability coverage
Registry records tagged Epigenomics, counted by capability.
Accessible data table
| Capability | Records |
|---|---|
| Knowledge | 3 |
| Evidence synthesis | 1 |
| Retrieval | 4 |
| Prediction | 8 |
| Classification | 8 |
| Regression | 2 |
| Design | 1 |
| Data analysis | 6 |
| Coding | 4 |
| Tool use | 5 |
| Experiment planning | 1 |
| Troubleshooting | 1 |
| Scientific reasoning | 8 |
Scientific Tasks in this domain
Task mappings are evidence-backed and may be partial for mixed suites.
Coverage-gap reading: zero counts indicate a gap in this registry, not proof that no benchmark exists. Propose a primary source through the contribution form.