suite · audited-with-caveats · verified 2026-08-13

Single-cell Omics Arena

A benchmark for evaluating LLM cell-type annotation across scRNA-seq and single-cell multiomics data.

Audited with caveats: 4 field(s) are marked provisional or conflicted. Warnings are shown next to affected values and these claims are excluded from unqualified comparisons.

Benchmark definition

What is counted

Version
initial-release
Total
1226 (Benchmark-wide cell-type annotation task total reported in the abstract.)
Task formats
unclassified
Capabilities
ClassificationScientific reasoning
Modalities
TextRaw omics

Version history

VersionStatusRelease / as-ofTotalFormal tracks
initial-release
single-cell-omics-arena-soar-initial-release-version
current2025-11-241226 (Benchmark-wide cell-type annotation task total reported in the abstract.)None registered

Tracks and subsets

IDCountBasisPartition?Notes
SOAR-RNA cell-type annotation tasks after preprocessing
soar-rna
1191SOAR-RNA benchmark entries are reported by their annotated cell types after preprocessing.No

Scientific Task Atlas

Scientific task classification

partial for initial-release. Only high-confidence Scientific Tasks explicitly supported by the creator source are mapped.

Scientific taskCoverageCountMappingEvidence
Cell-type annotationexplicitly-in-scope1226 tasks
Benchmark-wide cell-type annotation task total reported by the creator paper.
official-taxonomy
high confidence
single-cell-omics-arena-soar-automated-task-1-evidence

Relationship registry

How works use this benchmark

Partial claims, non-evaluation uses, and third-party summaries stay visible without entering model comparisons.

Normalized evaluations

evaluation

soar-e5d2b3e-rna-zero-shot-cot-use

Normalizedsubset · n=1191

Work: Single-cell Omics Arena repository result snapshot · source version single-cell-omics-arena-soar-repository-result-snapshot-e5d2b3e

Selection
formal-subset · All 1,191 records in the pinned SOAR-RNA JSON artifact, iterated in repository order with shuffle disabled.
Metrics
R-1, R-2, R-L, MET., B-1, B-2, BLEU

Not reported / unresolved: repeat count; confidence intervals; contamination or decontamination analysis

Official commit-pinned SOAR-RNA two-call zero-shot chain-of-thought result snapshot; the run covers the formal SOAR-RNA subset, not the full SOAR suite.

Evidence
  • repository-path: readme.md; soar_benchmark/configs/cell_type_annotation/experiment_soar_rna.py; soar_benchmark/task.py; soar_benchmark/datasets/soar_rna.json at commit e5d2b3e2619cb56fece5fba78fae989a67fd0c13 (SOAR-RNA zero-shot CoT relation, exact models, formal subset scope, metrics, and linked run.)
    Supports: /benchmark_version, /relation_type, /status, /model_ids, /scope, /metric_labels, /evaluation_run_ids, /reporting_gaps, /notes

evaluation

soar-e5d2b3e-rna-zero-shot-use

Normalizedsubset · n=1191

Work: Single-cell Omics Arena repository result snapshot · source version single-cell-omics-arena-soar-repository-result-snapshot-e5d2b3e

Selection
formal-subset · All 1,191 records in the pinned SOAR-RNA JSON artifact, iterated in repository order with shuffle disabled.
Metrics
R-1, R-2, R-L, MET., B-1, B-2, BLEU

Not reported / unresolved: repeat count; confidence intervals; contamination or decontamination analysis

Official commit-pinned SOAR-RNA zero-shot result snapshot; the run covers the formal SOAR-RNA subset, not the full SOAR suite.

Evidence
  • repository-path: readme.md; soar_benchmark/configs/cell_type_annotation/experiment_soar_rna.py; soar_benchmark/datasets/soar_rna.json at commit e5d2b3e2619cb56fece5fba78fae989a67fd0c13 (SOAR-RNA zero-shot relation, exact models, formal subset scope, metrics, and linked run.)
    Supports: /benchmark_version, /relation_type, /status, /model_ids, /scope, /metric_labels, /evaluation_run_ids, /reporting_gaps, /notes

Creation, training, validation, or model-selection uses

benchmark creation

single-cell-omics-arena-evaluation-of-large-language-m-single-cell-omics-arena-soar-1-use

Non-evaluationunknown

Work: Single-cell omics arena: evaluation of large language models for automatic cell-type annotations on single-cell omics data via RNA-seq bridging · source version single-cell-omics-arena-evaluation-of-large-language-m-pmc-version-1

Selection
not applicable
Models
Not reported / not applicable
Metrics
Not reported / not applicable
Linked runs
None

Not reported / unresolved: No benchmark version is reported.; The benchmark release date is not separately reported.; The official repository license is not reported.; A standalone SOAR-MultiOmics aggregate task count is not printed; PBMC and PFC counts are reported separately.; The source does not describe a separately released grader artifact.

AI-assisted double-pass extraction; values are limited to independently supported claims.

Evidence
  • section: Introduction
    Supports: /relation_type, /benchmark_id

Evaluation registry

Works and run settings

A setting change—scope, prompt, tools, budget, grader, or repeats—creates a separate run. Charts never cross a comparability group.

Evaluation run

soar-e5d2b3e-rna-zero-shot

From Single-cell Omics Arena repository result snapshot

soar-e5d2b3e-rna-zero-shotvinitial-release

Evaluated models / systems: gpt-4o-2024-05-13, gpt-4o-mini-2024-07-18

Scopesubset · n=1191
Shots0
Turnssingle-turn
System prompt publicYes
Reasoning / effortnone
BrowserNo
InternetNo
DatabasesNo
Code executionNo
ContainerNo
External tools
Token budget1024 maximum output tokens
Time / cost budgetNot reported
Temperature0
SeedNot reported
RepeatsNot reported
Graderautomatic evaluate-library text-overlap metrics · human review: not reported
Statisticsmetrics computed over all predictions and normalized references
ContaminationNot reported
Metrics, results, and full protocol

Metrics

MetricKind / baselineUnitAggregationThreshold / tolerance
R-1absolutesource-reported scoreall predictions and normalized referencesNot reported
R-2absolutesource-reported scoreall predictions and normalized referencesNot reported
R-Labsolutesource-reported scoreall predictions and normalized referencesNot reported
MET.absolutesource-reported scoreall predictions and normalized referencesNot reported
B-1absolutesource-reported scoreall predictions and normalized references; maximum order twoNot reported
B-2absolutesource-reported scoreall predictions and normalized references; maximum order twoNot reported
BLEUabsolutesource-reported scoregeometric average through order two over all predictions and normalized referencesNot reported

Results

ModelMetricValuen
gpt-4o-mini-2024-07-18R-152.63 source-reported score
SOAR-RNA zero-shot README table.
1191
gpt-4o-mini-2024-07-18R-227.45 source-reported score
SOAR-RNA zero-shot README table.
1191
gpt-4o-mini-2024-07-18R-L52.26 source-reported score
SOAR-RNA zero-shot README table.
1191
gpt-4o-mini-2024-07-18MET.41.08 source-reported score
SOAR-RNA zero-shot README table.
1191
gpt-4o-mini-2024-07-18B-145.74 source-reported score
SOAR-RNA zero-shot README table.
1191
gpt-4o-mini-2024-07-18B-223.29 source-reported score
SOAR-RNA zero-shot README table.
1191
gpt-4o-mini-2024-07-18BLEU32.64 source-reported score
SOAR-RNA zero-shot README table.
1191
gpt-4o-2024-05-13R-158.45 source-reported score
SOAR-RNA zero-shot README table.
1191
gpt-4o-2024-05-13R-232.07 source-reported score
SOAR-RNA zero-shot README table.
1191
gpt-4o-2024-05-13R-L58.12 source-reported score
SOAR-RNA zero-shot README table.
1191
gpt-4o-2024-05-13MET.45.39 source-reported score
SOAR-RNA zero-shot README table.
1191
gpt-4o-2024-05-13B-162.85 source-reported score
SOAR-RNA zero-shot README table.
1191
gpt-4o-2024-05-13B-242.68 source-reported score
SOAR-RNA zero-shot README table.
1191
gpt-4o-2024-05-13BLEU51.79 source-reported score
SOAR-RNA zero-shot README table.
1191

Evidence

  • repository-path: soar_benchmark/datasets/soar_rna.json; soar_benchmark/configs/cell_type_annotation/experiment_soar_rna.py; soar_benchmark/task.py; soar_benchmark/pipeline.py; soar_benchmark/prompt_templates/factory.py; analysis/cell_type_annotation/eval_multiple.py at commit e5d2b3e2619cb56fece5fba78fae989a67fd0c13 (Scope, exact models, zero-shot prompt, model call, budgets, tools, and automatic metric implementation.) — supports /benchmark_version, /scope, /model_ids, /protocol, /metrics
  • repository-path: readme.md, SOAR-RNA Benchmark, Zero-shot Cell Type Annotation table at commit e5d2b3e2619cb56fece5fba78fae989a67fd0c13 (Exact GPT-4o and GPT-4o mini values for the seven printed metrics.) — supports /results

Evaluation run

soar-e5d2b3e-rna-zero-shot-cot

From Single-cell Omics Arena repository result snapshot

soar-e5d2b3e-rna-zero-shot-cotvinitial-release

Evaluated models / systems: gpt-4o-2024-05-13, gpt-4o-mini-2024-07-18

Scopesubset · n=1191
Shots0
Turnstwo model calls
System prompt publicYes
Reasoning / effortzero-shot chain-of-thought
BrowserNo
InternetNo
DatabasesNo
Code executionNo
ContainerNo
External tools
Token budget1024 maximum output tokens per call; two calls per example
Time / cost budgetNot reported
Temperature0
SeedNot reported
RepeatsNot reported
Graderautomatic evaluate-library text-overlap metrics · human review: not reported
Statisticsmetrics computed over all predictions and normalized references
ContaminationNot reported
Metrics, results, and full protocol

Metrics

MetricKind / baselineUnitAggregationThreshold / tolerance
R-1absolutesource-reported scoreall predictions and normalized referencesNot reported
R-2absolutesource-reported scoreall predictions and normalized referencesNot reported
R-Labsolutesource-reported scoreall predictions and normalized referencesNot reported
MET.absolutesource-reported scoreall predictions and normalized referencesNot reported
B-1absolutesource-reported scoreall predictions and normalized references; maximum order twoNot reported
B-2absolutesource-reported scoreall predictions and normalized references; maximum order twoNot reported
BLEUabsolutesource-reported scoregeometric average through order two over all predictions and normalized referencesNot reported

Results

ModelMetricValuen
gpt-4o-mini-2024-07-18R-151.63 source-reported score
SOAR-RNA zero-shot CoT README table.
1191
gpt-4o-mini-2024-07-18R-226.6 source-reported score
SOAR-RNA zero-shot CoT README table.
1191
gpt-4o-mini-2024-07-18R-L51.17 source-reported score
SOAR-RNA zero-shot CoT README table.
1191
gpt-4o-mini-2024-07-18MET.40.84 source-reported score
SOAR-RNA zero-shot CoT README table.
1191
gpt-4o-mini-2024-07-18B-150.29 source-reported score
SOAR-RNA zero-shot CoT README table.
1191
gpt-4o-mini-2024-07-18B-227.89 source-reported score
SOAR-RNA zero-shot CoT README table.
1191
gpt-4o-mini-2024-07-18BLEU37.45 source-reported score
SOAR-RNA zero-shot CoT README table.
1191
gpt-4o-2024-05-13R-157.67 source-reported score
SOAR-RNA zero-shot CoT README table.
1191
gpt-4o-2024-05-13R-231.55 source-reported score
SOAR-RNA zero-shot CoT README table.
1191
gpt-4o-2024-05-13R-L57.34 source-reported score
SOAR-RNA zero-shot CoT README table.
1191
gpt-4o-2024-05-13MET.45.36 source-reported score
SOAR-RNA zero-shot CoT README table.
1191
gpt-4o-2024-05-13B-155.27 source-reported score
SOAR-RNA zero-shot CoT README table.
1191
gpt-4o-2024-05-13B-232.15 source-reported score
SOAR-RNA zero-shot CoT README table.
1191
gpt-4o-2024-05-13BLEU42.15 source-reported score
SOAR-RNA zero-shot CoT README table.
1191

Evidence

  • repository-path: soar_benchmark/datasets/soar_rna.json; soar_benchmark/configs/cell_type_annotation/experiment_soar_rna.py; soar_benchmark/task.py; soar_benchmark/pipeline.py; soar_benchmark/prompt_templates/factory.py; analysis/cell_type_annotation/eval_multiple.py at commit e5d2b3e2619cb56fece5fba78fae989a67fd0c13 (Scope, exact models, two-call CoT prompt, model calls, budgets, tools, and automatic metric implementation.) — supports /benchmark_version, /scope, /model_ids, /protocol, /metrics
  • repository-path: readme.md, SOAR-RNA Benchmark, Zero-shot Chain-of-thought Cell Type Annotation table at commit e5d2b3e2619cb56fece5fba78fae989a67fd0c13 (Exact GPT-4o and GPT-4o mini values for the seven printed metrics.) — supports /results

Comparable result views

R-1

soar-e5d2b3e-rna-zero-shot · soar-e5d2b3e-rna-zero-shot

CSV ↓
Accessible data table
ModelValueComparability group
gpt-4o-mini-2024-07-1852.63soar-e5d2b3e-rna-zero-shot
gpt-4o-2024-05-1358.45soar-e5d2b3e-rna-zero-shot

R-2

soar-e5d2b3e-rna-zero-shot · soar-e5d2b3e-rna-zero-shot

CSV ↓
Accessible data table
ModelValueComparability group
gpt-4o-mini-2024-07-1827.45soar-e5d2b3e-rna-zero-shot
gpt-4o-2024-05-1332.07soar-e5d2b3e-rna-zero-shot

R-L

soar-e5d2b3e-rna-zero-shot · soar-e5d2b3e-rna-zero-shot

CSV ↓
Accessible data table
ModelValueComparability group
gpt-4o-mini-2024-07-1852.26soar-e5d2b3e-rna-zero-shot
gpt-4o-2024-05-1358.12soar-e5d2b3e-rna-zero-shot

MET.

soar-e5d2b3e-rna-zero-shot · soar-e5d2b3e-rna-zero-shot

CSV ↓
Accessible data table
ModelValueComparability group
gpt-4o-mini-2024-07-1841.08soar-e5d2b3e-rna-zero-shot
gpt-4o-2024-05-1345.39soar-e5d2b3e-rna-zero-shot

B-1

soar-e5d2b3e-rna-zero-shot · soar-e5d2b3e-rna-zero-shot

CSV ↓
Accessible data table
ModelValueComparability group
gpt-4o-mini-2024-07-1845.74soar-e5d2b3e-rna-zero-shot
gpt-4o-2024-05-1362.85soar-e5d2b3e-rna-zero-shot

B-2

soar-e5d2b3e-rna-zero-shot · soar-e5d2b3e-rna-zero-shot

CSV ↓
Accessible data table
ModelValueComparability group
gpt-4o-mini-2024-07-1823.29soar-e5d2b3e-rna-zero-shot
gpt-4o-2024-05-1342.68soar-e5d2b3e-rna-zero-shot

BLEU

soar-e5d2b3e-rna-zero-shot · soar-e5d2b3e-rna-zero-shot

CSV ↓
Accessible data table
ModelValueComparability group
gpt-4o-mini-2024-07-1832.64soar-e5d2b3e-rna-zero-shot
gpt-4o-2024-05-1351.79soar-e5d2b3e-rna-zero-shot

R-1

soar-e5d2b3e-rna-zero-shot-cot · soar-e5d2b3e-rna-zero-shot-cot

CSV ↓
Accessible data table
ModelValueComparability group
gpt-4o-mini-2024-07-1851.63soar-e5d2b3e-rna-zero-shot-cot
gpt-4o-2024-05-1357.67soar-e5d2b3e-rna-zero-shot-cot

R-2

soar-e5d2b3e-rna-zero-shot-cot · soar-e5d2b3e-rna-zero-shot-cot

CSV ↓
Accessible data table
ModelValueComparability group
gpt-4o-mini-2024-07-1826.6soar-e5d2b3e-rna-zero-shot-cot
gpt-4o-2024-05-1331.55soar-e5d2b3e-rna-zero-shot-cot

R-L

soar-e5d2b3e-rna-zero-shot-cot · soar-e5d2b3e-rna-zero-shot-cot

CSV ↓
Accessible data table
ModelValueComparability group
gpt-4o-mini-2024-07-1851.17soar-e5d2b3e-rna-zero-shot-cot
gpt-4o-2024-05-1357.34soar-e5d2b3e-rna-zero-shot-cot

MET.

soar-e5d2b3e-rna-zero-shot-cot · soar-e5d2b3e-rna-zero-shot-cot

CSV ↓
Accessible data table
ModelValueComparability group
gpt-4o-mini-2024-07-1840.84soar-e5d2b3e-rna-zero-shot-cot
gpt-4o-2024-05-1345.36soar-e5d2b3e-rna-zero-shot-cot

B-1

soar-e5d2b3e-rna-zero-shot-cot · soar-e5d2b3e-rna-zero-shot-cot

CSV ↓
Accessible data table
ModelValueComparability group
gpt-4o-mini-2024-07-1850.29soar-e5d2b3e-rna-zero-shot-cot
gpt-4o-2024-05-1355.27soar-e5d2b3e-rna-zero-shot-cot

B-2

soar-e5d2b3e-rna-zero-shot-cot · soar-e5d2b3e-rna-zero-shot-cot

CSV ↓
Accessible data table
ModelValueComparability group
gpt-4o-mini-2024-07-1827.89soar-e5d2b3e-rna-zero-shot-cot
gpt-4o-2024-05-1332.15soar-e5d2b3e-rna-zero-shot-cot

BLEU

soar-e5d2b3e-rna-zero-shot-cot · soar-e5d2b3e-rna-zero-shot-cot

CSV ↓
Accessible data table
ModelValueComparability group
gpt-4o-mini-2024-07-1837.45soar-e5d2b3e-rna-zero-shot-cot
gpt-4o-2024-05-1342.15soar-e5d2b3e-rna-zero-shot-cot

Evidence and change history

Source locators remain visible; expand an item to inspect the exact Registry fields it supports.

Single-cell omics arena: evaluation of large language models for automatic cell-type annotations on single-cell omics data via RNA-seq bridging · section: Data availability · Supports 1 field

Open source →

  • /access/artifacts
Single-cell omics arena: evaluation of large language models for automatic cell-type annotations on single-cell omics data via RNA-seq bridging · section: Data availability · Supports 1 field

Open source →

  • /access/level
Single-cell omics arena: evaluation of large language models for automatic cell-type annotations on single-cell omics data via RNA-seq bridging · section: Data availability · Supports 1 field

Open source →

  • /access/tasks
Single-cell omics arena: evaluation of large language models for automatic cell-type annotations on single-cell omics data via RNA-seq bridging · section: Introduction · Supports 1 field

Open source →

  • /aliases
Single-cell omics arena: evaluation of large language models for automatic cell-type annotations on single-cell omics data via RNA-seq bridging · section: Introduction · Supports 1 field

Open source →

  • /capabilities
Single-cell omics arena: evaluation of large language models for automatic cell-type annotations on single-cell omics data via RNA-seq bridging · section: Evaluation benchmarks of SOAR-RNA and SOAR-MultiOmics · Supports 1 field

Open source →

  • /domains
Single-cell omics arena: evaluation of large language models for automatic cell-type annotations on single-cell omics data via RNA-seq bridging · section: Evaluation benchmarks of SOAR-RNA and SOAR-MultiOmics · Supports 1 field

Open source →

  • /kind
Single-cell omics arena: evaluation of large language models for automatic cell-type annotations on single-cell omics data via RNA-seq bridging · section: Method — prompting strategies and benchmark notation · Supports 1 field

Open source →

  • /modalities
Single-cell omics arena: evaluation of large language models for automatic cell-type annotations on single-cell omics data via RNA-seq bridging · section: Introduction · Supports 1 field

Open source →

  • /name
Single-cell omics arena: evaluation of large language models for automatic cell-type annotations on single-cell omics data via RNA-seq bridging · other: Article metadata — author-affiliation mapping · Supports 1 field

Open source →

  • /organizations
Single-cell omics arena: evaluation of large language models for automatic cell-type annotations on single-cell omics data via RNA-seq bridging · section: Evaluation benchmarks of SOAR-RNA and SOAR-MultiOmics · Supports 1 field

Open source →

  • /summary
Single-cell omics arena: evaluation of large language models for automatic cell-type annotations on single-cell omics data via RNA-seq bridging · other: Crossref bibliographic metadata (Resolved from the canonical paper identifier during intake.) · Supports 2 fields

Open source →

  • /release_date
  • /versions/0/release_date
Single-cell omics arena: evaluation of large language models for automatic cell-type annotations on single-cell omics data via RNA-seq bridging · section: Introduction · Supports 4 fields

Open source →

  • /task_counts/total
  • /task_counts/basis
  • /versions/0/task_counts/total
  • /versions/0/task_counts/basis
Single-cell omics arena: evaluation of large language models for automatic cell-type annotations on single-cell omics data via RNA-seq bridging · section: SOAR-RNA — Cell-type normalization · Supports 4 fields

Open source →

  • /task_counts/subsets
  • /versions/0/task_counts/subsets
  • /task_counts/subsets/0
  • /versions/0/task_counts/subsets/0
Single-cell omics arena: evaluation of large language models for automatic cell-type annotations on single-cell omics data via RNA-seq bridging · section: Data availability · Supports 3 fields

Open source →

  • /resources
  • /implementations
  • /access/license
single-cell-omics-arena-soar-official-repository-resource · other: Repository tree at commit e5d2b3e2619cb56fece5fba78fae989a67fd0c13 (The pinned tree contains soar_benchmark/datasets/soar_rna.json and no SOAR-MultiOmics benchmark artifact.) · Supports 3 fields

Open source →

  • /access/level
  • /access/tasks
  • /access/artifacts
Single-cell omics arena: evaluation of large language models for automatic cell-type annotations on single-cell omics data via RNA-seq bridging · other: Article metadata and Introduction · Supports 1 field

Open source →

  • /resources/0
Single-cell omics arena: evaluation of large language models for automatic cell-type annotations on single-cell omics data via RNA-seq bridging · other: Article metadata and Introduction · Supports 2 fields

Open source →

  • /latest_version
  • /versions/0
Single-cell omics arena: evaluation of large language models for automatic cell-type annotations on single-cell omics data via RNA-seq bridging · section: Introduction · Supports 1 field

Open source →

  • /scientific_task_classification/entries/0

Unresolved field claims

  • /release_dateProvisional · medium — The creator source does not report a separate benchmark release date. The machine-readable value uses the version-of-record publication date as a proxy and must not be interpreted as an independently verified artifact release date.
    Evidence: single-cell-omics-arena-soar-automated-bibliographic-evidence
  • /versions/0/release_dateProvisional · medium — The initial-release snapshot is an Atlas label and its date uses the creator paper's version-of-record publication date because no formal benchmark version date is reported.
    Evidence: single-cell-omics-arena-soar-automated-bibliographic-evidence
  • /access/levelConflicted · high — The creator paper states that the benchmark datasets are publicly available, but the pinned official repository snapshot contains the SOAR-RNA artifact and no SOAR-MultiOmics benchmark artifact. The conservative Atlas value is partially-open pending a versioned MultiOmics release.
    Evidence: single-cell-omics-arena-soar-automated-metadata-2-evidence, single-cell-omics-arena-soar-pinned-repository-access-evidence
  • /access/licenseProvisional · high — The double-pass review verified the official resource identity but did not establish a redistributable benchmark license; the value remains null pending source-level license verification.
    Evidence: single-cell-omics-arena-soar-automated-resource-evidence

View source-level modification history on GitHub →