benchmark-dual human CRISPR-Cas9 library
A human CRISPR-Cas9 paired-guide library created to compare dual- and single-targeting strategies in loss-of-function screens.
Scientific domain
Assay design
实验与筛选
A human CRISPR-Cas9 paired-guide library created to compare dual- and single-targeting strategies in loss-of-function screens.
A human CRISPR-Cas9 guide-RNA library assembled to compare single-targeting library performance in loss-of-function screens.
Two-output regression of housekeeping and developmental enhancer activity from a DNA sequence, evaluated with separate Pearson correlations.
Regression of protein fluorescence from an amino-acid sequence, evaluated with Spearman rank correlation.
A practical biology-research suite of 2,457 multiple-choice questions across eight broad categories and 31 versioned task files, with public and private contamination-monitoring splits.
Troubleshoots intentionally modified published biological protocols by selecting steps that would repair the stated outcome.
Expert-authored, artifact-rich free-response tasks that evaluate realistic research judgment across applied life-science workflows.
The original molecular-machine-learning benchmark of 17 dataset collections and more than 800 prediction endpoints spanning quantum, physicochemical, biophysical, and physiological properties.
Registry records tagged Assays and screening, counted by capability.
| Capability | Records |
|---|---|
| Knowledge | 1 |
| Evidence synthesis | 2 |
| Retrieval | 2 |
| Prediction | 6 |
| Classification | 2 |
| Regression | 3 |
| Design | 2 |
| Generation | 1 |
| Optimization | 1 |
| Data analysis | 2 |
| Tool use | 1 |
| Experiment planning | 2 |
| Troubleshooting | 3 |
| Scientific reasoning | 3 |
| Scientific communication | 1 |
Task mappings are evidence-backed and may be partial for mixed suites.