dataset · audited-with-caveats · verified 2026-08-02
benchmark human CRISPR-Cas9 library
A human CRISPR-Cas9 guide-RNA library assembled to compare single-targeting library performance in loss-of-function screens.
Audited with caveats: 2 field(s) are marked provisional or conflicted. Warnings are shown next to affected values and these claims are excluded from unqualified comparisons.
Benchmark definition
What is counted
- Version
- initial-release
- Total
- Not reported (The source names the complete library but does not print its original total gRNA inventory.)
- Task formats
- unclassified
- Modalities
DNA or RNA sequenceWet-lab output
Version history
| Version | Status | Release / as-of | Total | Formal tracks |
|---|
initial-release
benchmark-human-crispr-cas9-library-initial-release-version | current | 2025-02-26 | Not reported (The source names the complete library but does not print its original total gRNA inventory.) | None registered |
Scientific Task Atlas
Scientific task classification
partial for initial-release. Candidate artifact-derived Scientific Task mappings lacked an official artifact-level locator and were omitted; task mapping remains pending a targeted official-artifact audit.
The source names only a broad direction; no more specific leaf task can be assigned without inference.
Relationship registry
How works use this benchmark
Partial claims, non-evaluation uses, and third-party summaries stay visible without entering model comparisons.
Partial evaluation claims
evaluation
a-benchmark-comparison-of-crisprn-guide-rna-design-alg-benchmark-human-crispr-cas9-library-2-use
Partialunknown
Work: A benchmark comparison of CRISPRn guide-RNA design algorithms and generation of small single and dual-targeting libraries to boost screening efficiency · source version a-benchmark-comparison-of-crisprn-guide-rna-design-alg-pmc-version-1
- Selection
- not reported
- Models
- Not reported / not applicable
- Metrics
- log2 fold-change, Chronos gene fitness estimate, Spearman’s rho, Wilcoxon two-sample test P-value, genes targeted by both MinLib guides, genes with at least one corresponding guide in MinLib
- Linked runs
- None
Not reported / unresolved: The benchmark version and realized gRNA count are not reported.; Most performance values appear only in figures; no rasterized figure pages were supplied.; Run-level seeds and uncertainty intervals are not reported.; benchmark version; realized n/scope; exact model; numeric result
AI-assisted double-pass extraction; values are limited to independently supported claims.
Evidence
- section: Results and discussion, Par11
Supports: /relation_type - section: Results and discussion, Par11
Supports: /benchmark_id - figure: Figure 1 caption, panels a and c
Supports: /metric_labels - figure: Figure 1 caption, panel b
Supports: /metric_labels - figure: Figure 1 caption, panel c
Supports: /metric_labels - figure: Figure 1 caption, panel b
Supports: /metric_labels - section: Results and discussion, Par13
Supports: /metric_labels - section: Results and discussion, Par13
Supports: /metric_labels
Creation, training, validation, or model-selection uses
benchmark creation
a-benchmark-comparison-of-crisprn-guide-rna-design-alg-benchmark-human-crispr-cas9-library-1-use
Non-evaluationunknown
Work: A benchmark comparison of CRISPRn guide-RNA design algorithms and generation of small single and dual-targeting libraries to boost screening efficiency · source version a-benchmark-comparison-of-crisprn-guide-rna-design-alg-pmc-version-1
- Selection
- not applicable
- Models
- Not reported / not applicable
- Metrics
- Not reported / not applicable
- Linked runs
- None
Not reported / unresolved: The complete original gRNA inventory is not reported.; No benchmark version is reported.; The released dataset's license and version are not reported.
AI-assisted double-pass extraction; values are limited to independently supported claims.
Evidence
- section: Results and discussion, Par11
Supports: /relation_type - section: Results and discussion, Par11
Supports: /benchmark_id - section: Results and discussion, Par11
Supports: /scope - section: Methods, Library designs, Par19
Supports: /scope
Evaluation registry
Works and run settings
A setting change—scope, prompt, tools, budget, grader, or repeats—creates a separate run. Charts never cross a comparability group.
No normalized evaluation run is published yet. Creator evidence is still attached below.
Evidence and change history
Source locators remain visible; expand an item to inspect the exact Registry fields it supports.
A benchmark comparison of CRISPRn guide-RNA design algorithms and generation of small single and dual-targeting libraries to boost screening efficiency · section: Data availability · Supports 1 field
Open source →
A benchmark comparison of CRISPRn guide-RNA design algorithms and generation of small single and dual-targeting libraries to boost screening efficiency · section: Results and discussion, Par12 · Supports 1 field
Open source →
A benchmark comparison of CRISPRn guide-RNA design algorithms and generation of small single and dual-targeting libraries to boost screening efficiency · section: Abstract, Par9 · Supports 1 field
Open source →
A benchmark comparison of CRISPRn guide-RNA design algorithms and generation of small single and dual-targeting libraries to boost screening efficiency · section: Data availability · Supports 1 field
Open source →
A benchmark comparison of CRISPRn guide-RNA design algorithms and generation of small single and dual-targeting libraries to boost screening efficiency · section: Results and discussion, Par11 · Supports 1 field
Open source →
A benchmark comparison of CRISPRn guide-RNA design algorithms and generation of small single and dual-targeting libraries to boost screening efficiency · section: Results and discussion, Par11 · Supports 1 field
Open source →
A benchmark comparison of CRISPRn guide-RNA design algorithms and generation of small single and dual-targeting libraries to boost screening efficiency · section: Front matter: contrib-group and Aff1 · Supports 1 field
Open source →
A benchmark comparison of CRISPRn guide-RNA design algorithms and generation of small single and dual-targeting libraries to boost screening efficiency · section: Results and discussion, Par11 · Supports 1 field
Open source →
A benchmark comparison of CRISPRn guide-RNA design algorithms and generation of small single and dual-targeting libraries to boost screening efficiency · other: Crossref bibliographic metadata (Resolved from the canonical paper identifier during intake.) · Supports 1 field
Open source →
A benchmark comparison of CRISPRn guide-RNA design algorithms and generation of small single and dual-targeting libraries to boost screening efficiency · section: Results and discussion, Par11 · Supports 4 fields
Open source →
/task_counts/total/task_counts/basis/versions/0/task_counts/total/versions/0/task_counts/basis
A benchmark comparison of CRISPRn guide-RNA design algorithms and generation of small single and dual-targeting libraries to boost screening efficiency · section: Results and discussion, Par11 · Supports 2 fields
Open source →
/task_counts/subsets/versions/0/task_counts/subsets
A benchmark comparison of CRISPRn guide-RNA design algorithms and generation of small single and dual-targeting libraries to boost screening efficiency · section: Data availability · Supports 2 fields
Open source →
/resources/access/license
A benchmark comparison of CRISPRn guide-RNA design algorithms and generation of small single and dual-targeting libraries to boost screening efficiency · section: Front matter: article DOI · Supports 1 field
Open source →
A benchmark comparison of CRISPRn guide-RNA design algorithms and generation of small single and dual-targeting libraries to boost screening efficiency · section: Front matter: article DOI · Supports 2 fields
Open source →
/latest_version/versions/0
Unresolved field claims
/task_counts/subsetsProvisional · high — The double-pass review did not establish an exhaustive formal-subset inventory; the empty list must not be interpreted as evidence that the benchmark has no subsets.
Evidence: benchmark-human-crispr-cas9-library-automated-subset-coverage-evidence/access/licenseProvisional · high — The double-pass review verified the official resource identity but did not establish a redistributable benchmark license; the value remains null pending source-level license verification.
Evidence: benchmark-human-crispr-cas9-library-automated-resource-evidence
View source-level modification history on GitHub →