paper · benchmark creator
A benchmark comparison of CRISPRn guide-RNA design algorithms and generation of small single and dual-targeting libraries to boost screening efficiency
Joint Astrazeneca-Cancer Research Horizons Functional Genomics Centre · 2025-02-26
Relationship layer
Benchmark usage
This table records what the work did with each benchmark before attempting to normalize a run. Partial claims remain visible without being treated as comparable evaluations.
benchmark creation
a-benchmark-comparison-of-crisprn-guide-rna-design-alg-benchmark-dual-human-crispr-cas9-library-3-use
Non-evaluationunknown
Benchmark: benchmark-dual human CRISPR-Cas9 library · version Not reported
- Selection
- not applicable
- Models
- Not reported / not applicable
- Metrics
- Not reported / not applicable
- Linked runs
- None
Not reported / unresolved: No benchmark version is reported.; The final neutral-gene count is not printed after eight genes were removed.; The released dataset's license and version are not reported.
AI-assisted double-pass extraction; values are limited to independently supported claims.
Evidence
- section: Results and discussion, Par14
Supports: /relation_type - section: Results and discussion, Par14
Supports: /benchmark_id - section: Methods, Sec9, Par26
Supports: /scope - section: Methods, Sec9, Par26
Supports: /scope
evaluation
a-benchmark-comparison-of-crisprn-guide-rna-design-alg-benchmark-dual-human-crispr-cas9-library-4-use
Partialunknown
Benchmark: benchmark-dual human CRISPR-Cas9 library · version Not reported
- Selection
- not reported
- Models
- Not reported / not applicable
- Metrics
- log-fold changes, Chronos gene fitness estimate
- Linked runs
- None
Not reported / unresolved: The benchmark version is not reported.; The sample size and uncertainty for the reported −0.9 delta are not reported.; Other performance values appear only in figures; no rasterized figure pages were supplied.; Run-level seeds are not reported.; Conflicted metric claim omitted after independent verification; the evaluation relationship is published conservatively.; benchmark version; realized n/scope; exact model; numeric result
AI-assisted double-pass extraction; values are limited to independently supported claims.
Evidence
- section: Results and discussion, Par14
Supports: /relation_type - section: Results and discussion, Par14
Supports: /benchmark_id - section: Results and discussion, Par14
Supports: /metric_labels - section: Results and discussion, Par14
Supports: /metric_labels
benchmark creation
a-benchmark-comparison-of-crisprn-guide-rna-design-alg-benchmark-human-crispr-cas9-library-1-use
Non-evaluationunknown
Benchmark: benchmark human CRISPR-Cas9 library · version Not reported
- Selection
- not applicable
- Models
- Not reported / not applicable
- Metrics
- Not reported / not applicable
- Linked runs
- None
Not reported / unresolved: The complete original gRNA inventory is not reported.; No benchmark version is reported.; The released dataset's license and version are not reported.
AI-assisted double-pass extraction; values are limited to independently supported claims.
Evidence
- section: Results and discussion, Par11
Supports: /relation_type - section: Results and discussion, Par11
Supports: /benchmark_id - section: Results and discussion, Par11
Supports: /scope - section: Methods, Library designs, Par19
Supports: /scope
evaluation
a-benchmark-comparison-of-crisprn-guide-rna-design-alg-benchmark-human-crispr-cas9-library-2-use
Partialunknown
Benchmark: benchmark human CRISPR-Cas9 library · version Not reported
- Selection
- not reported
- Models
- Not reported / not applicable
- Metrics
- log2 fold-change, Chronos gene fitness estimate, Spearman’s rho, Wilcoxon two-sample test P-value, genes targeted by both MinLib guides, genes with at least one corresponding guide in MinLib
- Linked runs
- None
Not reported / unresolved: The benchmark version and realized gRNA count are not reported.; Most performance values appear only in figures; no rasterized figure pages were supplied.; Run-level seeds and uncertainty intervals are not reported.; benchmark version; realized n/scope; exact model; numeric result
AI-assisted double-pass extraction; values are limited to independently supported claims.
Evidence
- section: Results and discussion, Par11
Supports: /relation_type - section: Results and discussion, Par11
Supports: /benchmark_id - figure: Figure 1 caption, panels a and c
Supports: /metric_labels - figure: Figure 1 caption, panel b
Supports: /metric_labels - figure: Figure 1 caption, panel c
Supports: /metric_labels - figure: Figure 1 caption, panel b
Supports: /metric_labels - section: Results and discussion, Par13
Supports: /metric_labels - section: Results and discussion, Par13
Supports: /metric_labels
Normalized evaluation runs
This source has no normalized model run. It may be a creator-only source or a partial/non-evaluation benchmark use.