track · audited-with-caveats · verified 2026-07-21

ProteinGym DMS Indels

ProteinGym track for predicting experimental fitness measurements of insertion and deletion mutants across deep-mutational-scanning assays.

Audited with caveats: 2 field(s) are marked provisional or conflicted. Warnings are shown next to affected values and these claims are excluded from unqualified comparisons.

Benchmark definition

What is counted

Version
1.3
Total
66Conflicted · medium (DMS assays)
Task formats
zero-shot mutation-effect prediction; supervised mutation-effect prediction
Capabilities
PredictionRegressionClassificationDesignOptimization
Modalities
Protein sequenceTable

Version history

VersionStatusRelease / as-ofTotalFormal tracks
1.0
proteingym-dms-indel-v10
superseded2023-12-0866 (DMS assays)None registered
1.3
proteingym-dms-indel-v13
current2025-04-2766Conflicted · medium (DMS assays)None registered

Tracks and subsets

IDCountBasisPartition?Notes
Binding function category
binding-function-assays
0assaysNoNeither Table A2 nor the v1.3 coarse_selection_type field contains an indel Binding assay.

Scientific Task Atlas

Scientific task classification

complete for 1.3. Formal DMS indel track; source conflicts on assay count remain flagged on the benchmark.

Scientific taskCoverageCountMappingEvidence
Protein mutation-effect predictionexplicitly-in-scope66 assays
DMS assays.
official-track
high confidence
proteingym-dms-indel-evidence-v13
The underlying benchmark field carries the audit caveat.
Protein fitness predictionexplicitly-in-scope66 assays
DMS assays.
official-track
high confidence
proteingym-dms-indel-evidence-v13
Overlapping claim; not an additive task total.

Scientific coverage notes

DomainCoverageCountInterpretation
Protein designexplicitly-in-scopeNot reportedThe track uses fitness-prediction and design-oriented metrics, but design is not a separately counted subset.
Protein-protein bindingnot-in-scope0The official generic Binding function category contains zero indel assays in the paper and current reference file.
Protein-ligand bindingnot-in-scope0The official generic Binding function category contains zero indel assays in the paper and current reference file.

Evaluation registry

Works and run settings

A setting change—scope, prompt, tools, budget, grader, or repeats—creates a separate run. Charts never cross a comparability group.

No normalized evaluation run is published yet. Creator evidence is still attached below.

Evidence and change history

Source locators remain visible; expand an item to inspect the exact Registry fields it supports.

ProteinGym: Large-Scale Benchmarks for Protein Fitness Prediction and Design · section: pp. 1–10, Figure 1 and Sections 3–5 (Track definition, parent relationship, domains, modalities, formats, capabilities, and access.) · Supports 10 fields

Open source →

  • /name
  • /organizations
  • /release_date
  • /latest_version
  • /kind
  • /summary
  • /domains
  • /capabilities
  • /modalities
  • /task_formats
ProteinGym: Large-Scale Benchmarks for Protein Fitness Prediction and Design · table: pp. 6, 29–30; Tables 1, A1, and A2 (66 v1.0 indel assays and zero Binding indel assays.) · Supports 3 fields

Open source →

  • /versions/0/task_counts/total
  • /versions/0/task_counts/basis
  • /versions/0/task_counts/subsets
proteingym-dms-indel-v13-resource · repository-path: DMS_indels.csv and DMS_ProteinGym_indels.zip in Zenodo record 15293562 (Both expose 66 assay records; no coarse_selection_type=Binding row.) · Supports 8 fields

Open source →

  • /task_counts/total
  • /task_counts/basis
  • /task_counts/subsets
  • /versions/1/task_counts/total
  • /versions/1/task_counts/basis
  • /versions/1/task_counts/subsets
  • /scientific_task_classification/entries/0
  • /scientific_task_classification/entries/1
proteingym-dms-indel-repository-resource · repository-path: README.md Overview at tag PG_v1.3 (States 74 DMS indel assays.) · Supports 2 fields

Open source →

  • /task_counts/total
  • /versions/1/task_counts/total
proteingym-dms-indel-repository-resource · repository-path: README.md Resources, Results, Usage and reproducibility, Releases, and License (Current version, downloads, public scoring, implementation pin, and MIT license.) · Supports 9 fields

Open source →

  • /latest_version
  • /access/level
  • /access/tasks
  • /access/artifacts
  • /access/grader
  • /access/license
  • /access/biosafety_notes
  • /resources
  • /implementations

Unresolved field claims

  • /task_counts/totalConflicted · medium — The v1.3 archive/reference file contains 66 assays while the official PG_v1.3 README states 74.
    Evidence: proteingym-dms-indel-evidence-v13, proteingym-dms-indel-evidence-readme
  • /versions/1/task_counts/totalConflicted · medium — The v1.3 archive/reference file contains 66 assays while the official PG_v1.3 README states 74.
    Evidence: proteingym-dms-indel-evidence-v13, proteingym-dms-indel-evidence-readme

View source-level modification history on GitHub →