D5 · Interaction & complexes

Aptamer–target affinity prediction

Predict aptamer binding to proteins or other targets.

T45DNA/RNA+targetregression/ranking

Task definition

Input granularity
aptamer plus target
Biological target
binding affinity
Output representation
Kd/enrichment/rank
ML formulation
regression/ranking
Counting notes
NR

Benchmark coverage

2 benchmarks cover this task

B38Numeric results available

EternaBench

Thirty-one chemical-mapping, riboswitch and external thermodynamic datasets; repository is archived but versioned and reproducible.

8 benchmark-wide protocols · 107 benchmark-wide rows (not a task subtotal)
B39No standard numeric protocol

AptaBench

6,289 DNA/RNA aptamer–ligand records with fixed stratified, ligand-disjoint and aptamer-disjoint five-fold protocols; anonymous pre-review status should be preserved.

0 benchmark-wide protocols · 0 benchmark-wide rows (not a task subtotal)

Evaluation protocols

3 protocol units

ProtocolTrackSplit / subsetComparability
PROT-B10-SYSTEMATIC-BINDING-RANKING-DASE-F1-B4592C9ASystematic Binding Ranking
NR
DAse
F1
official_board_comparable
external_data_policy;inference_budget
PROT-B10-SYSTEMATIC-BINDING-RANKING-TARDBP-F1-84E8EA43Systematic Binding Ranking
NR
TARDBP
F1
official_board_comparable
external_data_policy;inference_budget
PROT-B10-SYSTEMATIC-BINDING-RANKING-ISLETS-F1-E58AF200Systematic Binding Ranking
NR
ISLETS
F1
official_board_comparable
external_data_policy;inference_budget