D4 · Variant effect & evolution

RNA DMS effect prediction

Predict mutation effects across RNA deep-mutational-scanning assays.

T38RNAregression/ranking

Task definition

Input granularity
mutant sequence or mutation
Biological target
experimental RNA fitness/function
Output representation
continuous assay score
ML formulation
regression/ranking
Counting notes
NR

Benchmark coverage

3 benchmarks cover this task

B10Numeric results available

RNA-Scope

Board is public; DeepASmRNA and DeeReCT-PolyA/PAS are exposed as distinct tracks; verify exact release and frozen splits before comparative claims.

79 benchmark-wide protocols · 2,093 benchmark-wide rows (not a task subtotal)
B11Numeric results available

RNAGym

Three core tasks plus a task-family view of the ribozyme-assay subset; the subset track is separated from the aggregate DMS-effect track.

2 benchmark-wide protocols · 7 benchmark-wide rows (not a task subtotal)
B29No public numeric result

NABench

Large-scale nucleotide fitness benchmark; verify repository release before production adoption.

0 benchmark-wide protocols · 0 benchmark-wide rows (not a task subtotal)

Evaluation protocols

2 protocol units

ProtocolTrackSplit / subsetComparability
PROT-SUPP-B11-RNAGYM-T2fitness overall | RNAGym original benchmark table
B11-TR01
full RNAGym fitness benchmark aggregate
fitness overall across the source-defined assay collection
insufficient_protocol_detail
assay-level aggregation details;external_data_policy;inference_budget
PROT-SUPP-B11-BASEPROMPT-T2fitness overall | BasePrompt same-source table
B11-TR01
full RNAGym fitness benchmark aggregate
fitness overall across the source-defined assay collection
insufficient_protocol_detail
assay-level aggregation details;external_data_policy;inference_budget